JWH-030

In the following article the impact of JWH-030 on contemporary society will be analyzed. Since its emergence, JWH-030 has exerted a significant influence on various aspects of daily life, ranging from culture to economics. Throughout history, JWH-030 has been the subject of intense debate and discussion, awakening passions and generating social movements. In this sense, it is crucial to closely examine the causes and consequences of JWH-030's presence in our lives, as well as its potential to shape the future. With a multidisciplinary approach, this article seeks to offer a comprehensive vision of how JWH-030 has transformed and continues to transform the world in which we live.
JWH-030
Legal status
Legal status
Identifiers
  • Naphthalen-1-yl-(1-pentylpyrrol-3-yl)methanone
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H21NO
Molar mass291.394 g·mol−1
3D model (JSmol)
  • CCCCCn3cc(cc3)C(=O)c1cccc2ccccc12
  • InChI=1S/C20H21NO/c1-2-3-6-13-21-14-12-17(15-21)20(22)19-11-7-9-16-8-4-5-10-18(16)19/h4-5,7-12,14-15H,2-3,6,13H2,1H3
  • Key:VPBJQDBKZSHCPC-UHFFFAOYSA-N
  (verify)

JWH-030 is a research chemical which is a cannabinoid receptor agonist. It has analgesic effects and is used in scientific research. It is a partial agonist at CB1 receptors, with a Ki of 87 nM, making it roughly half the potency of THC. It was discovered and named after John W. Huffman.

In the United States, CB1 receptor agonists of the 3-(1-naphthoyl)pyrrole class such as JWH-030 are Schedule I Controlled Substances.

See also

References

  1. ^ Lainton JA, Huffman JW, Martin BR, Compton DR (February 1995). "1-Alkyl-3-(1-naphthoyl) pyrroles: A new class of cannabinoid". Tetrahedron Letters. 36 (9): 1401–4. doi:10.1016/0040-4039(95)00016-6.
  2. ^ Pertwee RG, Griffin G, Lainton JA, Huffman JW (September 1995). "Pharmacological characterization of three novel cannabinoid receptor agonists in the mouse isolated vas deferens". European Journal of Pharmacology. 284 (3): 241–7. doi:10.1016/0014-2999(95)00318-f. PMID 8666005.
  3. ^ Griffin G, Atkinson PJ, Showalter VM, Martin BR, Abood ME (May 1998). "Evaluation of cannabinoid receptor agonists and antagonists using the guanosine-5'-O-(3-thio)-triphosphate binding assay in rat cerebellar membranes". The Journal of Pharmacology and Experimental Therapeutics. 285 (2): 553–60. PMID 9580597.
  4. ^ 21 U.S.C. § 812: Schedules of controlled substances
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